Direct Flights from Knoxville

33 nonstop destinations you can reach direct from Knoxville TYS, ranked by how often they fly. Pick one to see airlines, schedule, and what to do when you land.

• AtlantaATLUS-GA
  Delta, Frontier~8/day
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• CharlotteCLTUS-NC
  American~7/day
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• DenverDENUS-CO
  Allegiant, Frontier, Southwest, United~3/day
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• PhiladelphiaPHLUS-PA
  American~3/day
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• DetroitDTWUS-MI
  Delta~2/day
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• Punta GordaPGDUS-FL
  Allegiant~1/day
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• Fort LauderdaleFLLUS-FL
  Allegiant~1/day
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• Pinellas ParkPIEUS-FL
  Allegiant~1/day
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• MinneapolisMSPUS-MN
  Allegiant, Delta~1/day
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• MiamiMIAUS-FL
  American~1/day
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• New HavenHVNUS-CT
  Avelo—
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• MemphisMEMUS-TN
  Allegiant—
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• Key WestEYWUS-FL
  Allegiant—
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• OrlandoMCOUS-FL
  Allegiant, Southwest—
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• Oklahoma CityOKCUS-OK
  American, Delta, United—
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• WashingtonBWIUS-MD
  Southwest—
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• DallasDALUS-TX
  Southwest—
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• DestinVPSUS-FL
  Allegiant—
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• Las VegasLASUS-NV
  Allegiant—
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• PhoenixPHXUS-AZ
  Allegiant—
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• South BendSBNUS-IN
  Allegiant—
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• Sarasota/BradentonSRQUS-FL
  Allegiant—
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• New YorkEWRUS-NJ
  Allegiant—
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• Gulf ShoresGUFUS-AL
  Allegiant—
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• BellevilleBLVUS-IL
  Allegiant—
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• JacksonvilleJAXUS-FL
  Allegiant—
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• ChicagoMDWUS-IL
  Allegiant—
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• GainesvilleGNVUS-FL
  Delta—
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• NashvilleBNAUS-TN
  Southwest—
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• BostonBOSUS-MA
  Allegiant—
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• HoustonHOUUS-TX
  Allegiant—
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• AustinAUSUS-TX
  Allegiant—
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• BirminghamBHMUS-AL
  Delta, United—
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